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No treatment-related adverse reactions were recorded in any of the studies. REVOLUTION is a quick-drying, non-greasy, waterproof spot on treatment for dogs and cats. Spot-ons. 12 or 6 mg/kg to 15 mg/kg, Spot On (topical), monthly. Selamectin is used to kill fleas (Ctenocephalides felis) and ear mites (Otodectis cynotis) in dogs and cats.It is also indicated for the treatment and control of sarcoptic mange … Search for more papers by this author. Clearkill SMT – Selamectin 12% Spot on for Flea, Ear Mite, Roundworm and Heartworm Diseases, 1 ml ₹ 690.00 ₹ 590.00 Clearkill SMT prevents and controls, flea, ear … On days 3, 10, 19, 25, and 31, each cat was infested by direct application of 20 fleas that fed on blood inoculated with B. henselae.Poly-merase chain reaction (PCR) on pooled fleas confirmed that It was shown that more than 90% of skin lesions had resolved 15 days after the first application, while clinical and parasitological cure was achieved by day 30. The safety of selamectin solution administered orally also was tested in case of accidental oral ingestion. Fourteen and 16 cats were randomly assigned to treatment groups in Studies 1 and 2, respectively. STRONGHOLD is a spot-on solution that contains the active substance selamectin, which belongs to a class of medicines having an antiparasitic action. The new spot-on formulation of selamectin plus sarolaner for cats administered topically at monthly intervals at the commercial dose range of 6.0–12.0 mg selamectin and 1.0–2.0 mg sarolaner per kg bodyweight, was safe and highly effective against natural infestations of fleas and ticks on cats. Do not massage the product into the skin. For treatment, doses of 13.6-18.75 mg/head of selamectin were administered in a topical preparation applied to a single spot on the skin on the back of the neck, and no side effects were observed. The efficacy of a new spot-on formulation of selamectin plus sarolaner for cats was evaluated against induced infections with Ancylostoma tubaeforme (hookworm) and Toxocara cati (roundworm). Ticks were counted 48h after treatment and after each re-infestation. Systemically active products include selamectin and fenthion. The cats in group 3 received a fluralaner treatment (Bravecto®spot-on solution for cats, MSD) at the minimum recommended dose of 40.0 mg/kg on Day 0. Selamectin was dispensed as a spot-on application at the skin of the neck, using a 1 ml syringe. Selamectin Spot-on a b s t r a c t In recent years Aelurostrongylus abstrusus has often been reported in Italy. The content of each tube is formulated to provide a minimum of 2.7 mg/lb (6 mg/kg) of body weight of selamectin. Cats in group 2 were treated with selamectin/sarolaner (Stronghold®Plus; Zoetis) at the minimum recommended dose of 1.0 mg/kg sarolaner and 6.0 mg/kg selamectin on Days 0, 30 and 60. F. Albanese. In this study, 17 rabbits from Greece with scabies were treated with selamectin spot on (Stronghold) at 8-14 mg/kg body weight twice at 30-day intervals. Comparative short-term efficacy of Oridermyl(®) auricular ointment and Revolution(®) selamectin spot-on against feline Otodectes cynotis and its associated secondary otitis externa. Part the hair at the base of the animal's neck in front of the shoulder blades to expose a small area of skin. Oral administration of selamectin solution at the recommended topical dose in 5- to 8-month-old beagles did not cause any adverse reactions. Efficacy of selamectin spot‐on formulation against Neotrombicula autumnalis in eight cats F. Leone. 409 Blood sampling Blood samples (5 ml each) were collected from the antebrachial vein into EDTA vacutainer tubes at 0 (pre-treatment), 0.16, 0.33, 0.5, 1, 1.5, 2, 3, 4, 6, 8, 10, 13, 15, 20, 25, 30 and 35 days after drug administration. Selamectin Topical Application: (mauve packet labeled for kittens, concentration listed above under Availability) 4 mg/kg to 8 mg/kg once per month or up to once every two weeks based on veterinary assessment. Stronghold (selamectin 6 % spot on solution) was administered on days 0 and 32. Eight rabbits were intact males while the rest were 5 females and 2 castrated males. Stronghold Spot-On Solution for cats and dogs is used to treat and prevent infestations of parasites that live on the skin or in the fur of cats and dogs, such as fleas and mites. Stronghold should be administered as a single application of a single dose delivering a minimum of 6 mg/kg selamectin. Please wait a moment while we find what you are looking for… Topical spot-on products are either absorbed systemically or distribute laterally and remain within the skin. Selamectin is a novel semi-synthetic avermectin (Figure 45.2), which is marketed as Revolution.Revolution is a topical antiparasitic preparation recommended for use in dogs and cats 6 weeks of age and older. selamectin oil composition caligus Prior art date 2013-02-26 Application number PCT/US2014/018506 Other languages French (fr) Inventor John Adam Wendt David Jose ASPER Stacy ROSS Original Assignee Zoetis Llc Priority date (The priority date is an assumption and is not a legal conclusion. Selehold (selamectin) A spot-on treatment for the effective control of fleas and roundworms. Four of the studies were designed to e … jroy@vetoquinol.ca Treatment consisted of administration of selamectin spot on topically at 1–3 occasions. Stronghold is presented in a single use plastic tube for cutaneous (spot-on) administration to dogs and cats. It has no unpleasant odour, and bathing your pet 2 hours after application does not reduce it's efficacy. Spot-on use. Follow the steps given in the video for best results of Clearkill Selamectin Spot On! It can also be used to treat worm parasites that live inside the body. Selamectin 60mg excipients q.s.p. One hundred and four cats from 65 different households were enrolled across the two studies. Selarid™ (selamectin) ... on the skin and squeeze the applicator 3 or 4 times to empty its entire contents directly onto the skin in one spot. The efficacy of a selamectin (Stronghold®) spot on treatment in the prevention of Bartonella henselae transmission by Ctenocephalides felis in cats, using a new high-challenge model May be used for fleas and lice. Five laboratory studies were conducted using adult, purpose-bred cats. The mean dose of selamectin used was 12.5 mgkg-1 (range 6.2 to 20.0). The safety and efficacy of a new spot-on formulation of selamectin plus sarolaner were evaluated for the treatment and control of natural flea infestations on cats in two non-randomised, multi-centre clinical trials conducted in 8 different locations in Queensland, Australia. Presentations A colourless to yellow ready to use solution of selamectin. One treatment for fleas lasts four weeks, the product also acts on eggs and larvae in the home to help prevent reinfestation. For subsequent re-infestations, efficacy was >97.9% for at least 3 weeks and was 89.0% after the re-infestation on Day 28. Dosage: 6 … Stronghold Spot On Solution. When concurrent infestations or infections in the same animal are to be treated, only one application of the recommended 6 mg/kg dose should be administered at any one time. This lungworm is very common in cat colonies due to its route of transmission. Revolution (selamectin) Topical Parasiticide is available as a colorless to yellow, ready to use solution in single dose tubes for topical (dermal) treatment of dogs . Clinica Veterinaria Adriatica, Senigallia (AN), Italy; Clinica Veterinaria L’Arca, Napoli, Italy. ... Spot-on use. Buy Xelamec® Spot On here. On the outside, on the inside. Shop with us at www.disinfecto.com A spot-on parasiticide containing sarolaner and selamectin was able to safely and successfully eliminate D cati mite infestation of the ear while sparing the application of any products directly into the ear canal that do not have a reliable safety profile in terms of ototoxicity. It is available as a spot-on solution in 2 different concentrations (6% and 12%) and in tubes of various strengths (15, 30, 45, 60, 120, 240 and 360 mg).The concentration and the strength to use depends on the weight and species of the animal being treated. No live mites were recovered from any selamectin-treated rabbit In a pre-clinical study selamectin was dosed orally to ivermectin-sensitive collies. Revolution is safe to use on puppies and kittens from 8 weeks of age. Check the applicator to ensure that it is empty. Remove the Stronghold pipette from its protective package. A second dose was applied on day 30 to ensure complete cure. 42 or 15 mg/kg, Spot On (topical). Deciding a therapeu-tic approach can be difficult in such colonies, because there is no certainty whether oral medicines The efficacy of a new spot-on formulation of selamectin/sarolaner was evaluated against induced Otodectes cynotis infestations in cats in two randomized, blinded studies. 1ml. The efficacy and safety of selamectin was assessed in rabbits naturally infested with Psoroptes cuniculi by McTier et al.23 Selamectin was applied onto the skin at the base of the neck to give a minimum dose-rate of 6 or 18 mg/kg body weight, either once or twice at 28 days apart. Topical high-concentration, low-volume preparations have been designed to increase both the convenience of treatment and compliance. Keeping the applicator squeezed, drag it away from the liquid and lift to remove. Each tube contains: SELAMECTIN. Clearkill SMT Selamectin 12% Spot on for Flea, Ear Mite, Roundworm and Heartworm Diseases, 1 ml Vivaldis Single Pipette Treatment Of Fleas, Ticks And Chewing Lice Infestation For Dogs Upt 0 - 10Kg Vivaldis Vi-Fi Forte (10-20 Kg) - Pack Of Single Pipettes : Spot On For Prevention & Treatment Of Fleas, Ticks And Chewing Lice Infestation Georges, Lavaltrie, Quebec J5T 3S5, Canada. six weeks of age and older and cats eight weeks of age and older. Two rabbits belonged to multi-rabbit households. Holding the pipette upright, firmly depress the cap to puncture the applicator seal, then remove the cap. All in-contact rabbits were treated. Stronghold is an antiparasitic medicine that contains the active substance selamectin. Roy J(1), Bédard C, Moreau M, Sauvé F. Author information: (1)Vétoquinol Canada, 2000 ch. The new spot-on formulation of selamectin plus sarolaner demonstrated 99.3% efficacy (P<0.0001) within 24h after treatment against pre-existing infestations. Stronghold Spot-On Solution for Cats & Dogs. Cats were treated on Day 0 with the spot-on formulation at the minimum recommended label dose of 6.0mg selamectin and 1.0mg sarolaner per kg bodyweight or with a placebo.

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